Background: Chromodomain helicase DNA-binding protein 5 (CHD5), which belongs to a superfamily of SWI2/SNF2-related ATPases, is a conventional tumor suppressor gene encoding a unique combination of functional domains followed by a helicase domain and a DNA-binding domain. To date, CHD5 protein was detected in brain region and appeared to be enriched in neurons.\n \nMethodology/Principal Findings: We genotyped CHD5 tagging single-nucleotide polymorphism (tSNP) rs1534997 by TaqMan probes in two independent cohorts: the discovery study including 264 cases and 255 controls (North China); and the replicative study including 477 cases and 471 controls (South China). The discovery cohort revealed that genotype AA in cases was less than that from controls (adjusted OR 0.62, 95% CI 0.42-0.91, P = 0.009). This protective quality increased in a dose-dependent manner as genotype AA decreased (Ptrend = 0.004). Corresponding relevance for genotype AA was showed in the replicative and combined cohorts (replicative: adjusted OR 0.58, 95% CI 0.44-0.79, P = 6.328×10-4, Ptrend = 2.053×10-4; Combined: adjusted OR 0.59, 95% CI 0.47-0.76, P = 7.167×10-5, Ptrend = 8.905×10-6). \n\nConclusion: Our study indicated that rs1534997 of CHD5 might protect against the risk of paranoid schizophrenia in a dose-dependent manner.

The author in a historical context showed the role of evolution of geopolitical roots in the formation of mentality of Russian mass consciousness. Regarding the Russian nation natural and geographical factor includes country’s location, climate and soil peculiarities, and territorial size of the state. That is why the factor of geopolitical location of Russia among other world countries played a significant role in formation of mass consciousness of the Russian nation. The Russian nation is forced by historical circumstances to settle down on a great plain located at the joint of Europe and Asia

Drought is the main environmental factor which limits crop productivity. The major cereals maize, rice and wheat exhibited a variety of proneness to water shortage. To develop drought tolerant varieties, different molecular and genetic approaches are being used but these approaches are time consuming and germplasm dependent. Many transcription factors are involved in stress responses. DREB1A transcription factor identifies the dehydration responsive elements and performs an essential role in stimulating the expression of drought tolerance enhancing genes in Arabidopsis thaliana. In our efforts to develop drought tolerance in a local high yielding wheat cultivar “Punjab-11”, AtDREB1A gene was cloned under rd29A promoter and transformed into wheat through Agrobacterium mediated method. Plants expressing DREB1A gene revealed significant resistance to drought stress in contrast with wild type plants in field under drought conditions. Seed germination results showed that transgenic seeds were able to germinate on 200 mM mannitol while control seeds were unable to germinate. Various physiological tests revealed higher drought stress tolerance in transgenic plants than their wild type counterparts. Transgenic plants exhibited higher plant height, more number of tillers per plant, more flag leaf area and more grain yield than control plants in field under drought condition. The current study showed that transgenic wheat cultivar “Punjab-11” performed better in field under drought stress conditions and increased the grain yield.

One hundred and twenty patients of lateral epicondylitis of 3 – 6 months duration in age group of 20 – 40 years were randomly distributed in three groups ( A, B and C) based on the treatment modality used in the three groups. Each study group enrolled 40 patients using block randomization. Group A patients received 2ml of corticosteroid injection, Group B 2ml of autologous blood and Group C 2ml of 5% dextrose. Patients were then followed at regular intervals till a final follow up at 6 months. The Visual analogue scale (VAS) scores were recorded at pre procedure and post procedure at 4 weeks and at 6 months. The study showed a significant difference in the scores among the three groups. The mean VAS scores changed at 4 weeks from a pre procedure mean of 7 to 3 in Group A, a mean of 8 to a mean of 5 in group B and a mean of 7 to 6 in group C. The mean VAS scores changed at 6 months from a pre procedure mean of 7 to 5 in Group A, a mean of 8 to 2 in group B and a mean of 7 to 5 in group C. These results showed an early improvement in Group A and B as compared to the control but better improvement of scores were seen in the autologous blood group at 6 months follow up. The results were analyzed statistically and the results were found to be statistically significant (p<.001) In this prospective, randomized, controlled trial, although corticosteroid showed an early advantage over the autologous blood group but at long term follow-up of 6 months results were much better for autologous blood group. It’s hence proposed that a combination of steroid followed later by an autologous blood injection would have the advantage of both the treatment modalities.

The objective of the broadband\nwireless technologies is to ensure the end to end Quality of Service (QoS) for the service classes.Wimax is a revolution in wireless networks,\nwhich could support real time multimedia\nservices. In order to provide QoS support and efficient usage of system resources an intelligent scheduling algorithm is needed. The design of the detailed scheduling algorithm is a\nmajor focus for researchers and service\nproviders. In this paper, a channel aware crosslayer scheduling algorithm for Wimax networks has been proposed. This scheme employs the Signal to Noise Ratio (SNR) value,which allocates the bandwidth based on the information about the quality of the channel,and the service requirements of each connection. The proposed algorithm is described in detail, and evaluated with one VOIP codec and real time video traffic,\nthrough a series of simulations. The QoS\nparameters of throughput, packet loss, average delay and average jitter have been measured in simulation.

Maize is one of the most important cereal crops grown worldwide. Aluminum toxicity and low pH are the two main important factors affecting maize production on the Ultisols of the tropics, including Malaysia. Two short-term experiments were conducted in a laboratory to investigate the effects of Al and/or pH on the growth of maize seedlings, using Mas Madu cultivar. In experiment 1, the seedlings were grown in 0.5 mM CaCl2 solution containing various concentration of Al for one week. In the second experiment, maize seedlings were grown in the same solution but at different pH levels. The morphology of the maize root was studied at harvest using a root scanner. Organic acids secretions from the roots were determined using high performance liquid chromatography. The results showed that root length and root surface area of the maize seedlings decreased significantly with increasing Al concentration, but the root length and root surface area increased with the increase in solution pH. Only oxalic acid was secreted by the maize roots, occurring mostly at high Al concentration as well as at very low pH. The secretion of this acid by the roots is a plausible mechanism how maize slightly defend itself against Al3+ toxicity and/or H+ stress. The critical Al concentration and pH as determined by this study were 12 µM and 6.2, respectively. It means that acid Ultisols in the tropics having high Al concentration should be adequately limed to eliminate Al toxicity before being used for sustainable maize cultivation.

With penetration of distributed energy sources and generation electricity from them in power systems, controlling the stability of network has been more complicated in recent years. In this respect, researchers showed a tendency to use different methodologies to simplify the control of network stability. Nowadays, engineers divide the distribution system to many subsystems which are called microgrid. A microgrid works in two different modes: grid-connected and island mode that require different methods to control. The control methods can be divided to two different forms, with communication and without communication. This paper is a short survey on controlling microgrids with distributed renewable energy resources especially in Island mode and discusses Multi-agent systems and droop characteristic strategies.